CHEM 560

Analysis of Dynamic Equilibrating Systems

This module has always been about practical lessons on methods for determining parameters like Kassoc, etc. The 201705 offering also included a brief (2-3 hour) overview of noncovalent interactions, because that material is no longer offered in any other graduate course or module. Please mention to Fraser if you'd like that covered in 2019.  

• Major topics are:
• A. Intro to dynamic systems and weak interactions
• B. Determining stoichiometry and Kassoc by NMR
• C. Determining thermodynamic parameters by NMR
• D. Determining assembly kinetics by NMR
• E. Student presentations on various extensions of these lessons to other techniques. Topics might include:
  • UV-Vis and Fluorescence,  
  • Stopped-flow methods,  
  • Line shape analysis,
  • Isothermal titration calorimetry,
  • Potentiometry,  or
  • other relevant topics that students want to bring to the class.

Please email fhof@uvic.ca if you’re interested in taking or auditing the class.

Dr. Hof will build the class list and figure out timing that works for everyone.